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mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells

Epidermal Growth Factor receptor (EGFR) is a tyrosine kinase receptor widely expressed on the surface of numerous cell types, which activates several downstream signalling pathways involved in cell proliferation, migration and survival. EGFR alterations, such as overexpression or mutations, have bee...

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Detalles Bibliográficos
Autores principales:	Colella, Barbara, Colardo, Mayra, Iannone, Gianna, Contadini, Claudia, Saiz-Ladera, Cristina, Fuoco, Claudia, Barilà, Daniela, Velasco, Guillermo, Segatto, Marco, Di Bartolomeo, Sabrina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464593/ https://www.ncbi.nlm.nih.gov/pubmed/32823532 http://dx.doi.org/10.3390/cancers12082266

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