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Senescence and Cancer: A Review of Clinical Implications of Senescence and Senotherapies
Cellular senescence is a key component of human aging that can be induced by a range of stimuli, including DNA damage, cellular stress, telomere shortening, and the activation of oncogenes. Senescence is generally regarded as a tumour suppressive process, both by preventing cancer cell proliferation...
Autores principales: | Wyld, Lynda, Bellantuono, Ilaria, Tchkonia, Tamara, Morgan, Jenna, Turner, Olivia, Foss, Fiona, George, Jayan, Danson, Sarah, Kirkland, James L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464619/ https://www.ncbi.nlm.nih.gov/pubmed/32752135 http://dx.doi.org/10.3390/cancers12082134 |
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