Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson’s Disease

Astrocytic dysfunction has been implicated in Parkinson’s disease (PD) pathogenesis. While the Tumor necrosis factor-like weak inducer of apoptosis (TWEAK)/Fn14 signaling axis is known to play a role in PD-like neuropathology, the molecular mechanisms that govern this process remain poorly understoo...

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Detalles Bibliográficos
Autores principales: Samidurai, Manikandan, Tarale, Prashant, Janarthanam, Chelva, Estrada, Crystal Gomez, Gordon, Richard, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464730/
https://www.ncbi.nlm.nih.gov/pubmed/32759670
http://dx.doi.org/10.3390/cells9081831

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