Cargando…

SMAD4 Overexpression in Patients with Sleep Apnoea May Be Associated with Cardiometabolic Comorbidities

Obstructive sleep apnoea (OSA) is associated with several diseases related to metabolic and cardiovascular risk. Although the mechanisms involved in the development of these disorders may vary, OSA patients frequently present an increase in transforming growth factor beta (TGFβ), the activity of whi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Díaz-García, Elena, Jaureguizar, Ana, Casitas, Raquel, García-Tovar, Sara, Sánchez-Sánchez, Begoña, Zamarrón, Ester, López-Collazo, Eduardo, García-Río, Francisco, Cubillos-Zapata, Carolina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464800/ https://www.ncbi.nlm.nih.gov/pubmed/32722512 http://dx.doi.org/10.3390/jcm9082378

Ejemplares similares

Intermittent Hypoxia Mediates Paraspeckle Protein-1 Upregulation in Sleep Apnea
por: Díaz-García, Elena, et al.
Publicado: (2021)

Upregulated Proteasome Subunits in COVID-19 Patients: A Link with Hypoxemia, Lymphopenia and Inflammation
por: Alfaro, Enrique, et al.
Publicado: (2022)

SMAD4 Expression in Monocytes as a Potential Biomarker for Atherosclerosis Risk in Patients with Obstructive Sleep Apnea
por: Díaz-García, Elena, et al.
Publicado: (2023)

Impaired Kallikrein-Kinin System in COVID-19 Patients' Severity
por: Alfaro, Enrique, et al.
Publicado: (2022)

Sleep and cardiometabolic comorbidities in the obstructive sleep apnoea–COPD overlap syndrome: data from the European Sleep Apnoea Database
por: van Zeller, Mafalda, et al.
Publicado: (2023)

Obstructive Sleep Apnea Monocytes Exhibit High Levels of Vascular Endothelial Growth Factor Secretion, Augmenting Tumor Progression
por: Cubillos-Zapata, Carolina, et al.
Publicado: (2018)

NLRP3 Inflammasome Overactivation in Patients with Aneurysmal Subarachnoid Hemorrhage
por: Díaz-García, Elena, et al.
Publicado: (2022)

Role of CD39 in COVID-19 Severity: Dysregulation of Purinergic Signaling and Thromboinflammation
por: Díaz-García, Elena, et al.
Publicado: (2022)

Reply to Chen et al.
por: Zamarrón, Ester, et al.
Publicado: (2023)

PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea
por: Díaz-García, Elena, et al.
Publicado: (2023)

Bidirectional relationships of comorbidity with obstructive sleep apnoea
por: Gleeson, Margaret, et al.
Publicado: (2022)

Obstructive sleep apnea is associated with impaired renal function in patients with diabetic kidney disease
por: Zamarrón, Ester, et al.
Publicado: (2021)

Clinical Phenotypes and Comorbidity in European Sleep Apnoea Patients
por: Saaresranta, Tarja, et al.
Publicado: (2016)

Cardiovascular and metabolic comorbidities in patients with obstructive sleep apnoea syndrome
por: FUSETTI, M., et al.
Publicado: (2012)

Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL
por: Zhang, Yuan, et al.
Publicado: (2022)

Circulating levels of vascular endothelial markers in obstructive sleep apnoea syndrome. Effects of nasal continuous positive airway pressure
por: Zamarrón, Carlos, et al.
Publicado: (2011)

Multimorbidity and overall comorbidity of sleep apnoea: a Finnish nationwide study
por: Palomäki, Marja, et al.
Publicado: (2022)

Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100
por: Toledano, Víctor, et al.
Publicado: (2015)

Epigenetics of Subcellular Structure Functioning in the Origin of Risk or Resilience to Comorbidity of Neuropsychiatric and Cardiometabolic Disorders
por: Zapata-Martín del Campo, Carlos Manuel, et al.
Publicado: (2018)

Prevalence and impact of comorbid obstructive sleep apnoea in diffuse parenchymal lung diseases
por: Li, Diandian, et al.
Publicado: (2021)

The Burden of Respiratory Alterations during Sleep on Comorbidities in Obstructive Sleep Apnoea (OSA)
por: Tondo, Pasquale, et al.
Publicado: (2022)

Cardiometabolic Comorbidities in Psoriasis and Psoriatic Arthritis
por: Puig, Lluís
Publicado: (2017)

Continuous positive airway pressure adherence declines with age in elderly obstructive sleep apnoea patients
por: Martinez-Garcia, Miguel Angel, et al.
Publicado: (2019)

Treatment with CPAP in Elderly Patients with Obstructive Sleep Apnoea
por: Posadas, Tomas, et al.
Publicado: (2020)

Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma
por: Cubillos-Zapata, Carolina, et al.
Publicado: (2020)

Small airway dysfunction in smokers with stable ischemic heart disease
por: Llontop, Claudia, et al.
Publicado: (2017)

An Improved Model of Moderate Sleep Apnoea for Investigating Its Effect as a Comorbidity on Neurodegenerative Disease
por: Roberts, Reno, et al.
Publicado: (2022)

Sleep apnoea
por: Jun, Jonathan C., et al.
Publicado: (2016)

Sleep Apnoea
por: Wight, Jeremy
Publicado: (1999)

Sleep Apnoea
por: Wright, John, et al.
Publicado: (1999)

Prognostic Value of the Six-Second Spirometry in Patients with Chronic Obstructive Pulmonary Disease: A Cohort Study
por: Prats, Eva, et al.
Publicado: (2015)

Intraarticular overexpression of Smad7 ameliorates experimental arthritis
por: Chen, Shih-Yao, et al.
Publicado: (2016)

Potential Pathophysiological Pathways in the Complex Relationships between OSA and Cancer
por: Sánchez-de-la-Torre, Manuel, et al.
Publicado: (2023)

Effects of photodynamic therapy on dermal fibroblasts from xeroderma pigmentosum and Gorlin-Goltz syndrome patients
por: Zamarrón, Alicia, et al.
Publicado: (2017)

Is There Evidence of Early Vascular Disease in Patients with Obstructive Sleep Apnoea Without Known Comorbidities? Preliminary Findings
por: Steiropoulos, P, et al.
Publicado: (2013)

O013 The pathogenesis of obstructive sleep apnea in individuals with comorbid insomnia and obstructive sleep apnoea (COMISA)
por: Brooker, E, et al.
Publicado: (2021)

Variants of PCSK9 Gene Are Associated with Subclinical Atherosclerosis and Cardiometabolic Parameters in Mexicans. The GEA Project
por: Zamarrón-Licona, Erasmo, et al.
Publicado: (2021)

Non-invasive ventilation in obesity hypoventilation syndrome without severe obstructive sleep apnoea
por: Masa, Juan F, et al.
Publicado: (2016)

Presbyvestibulopathy, Comorbidities, and Perception of Disability: A Cross-Sectional Study
por: Soto-Varela, Andrés, et al.
Publicado: (2020)

Smad4 Loss Synergizes with TGFα Overexpression in Promoting Pancreatic Metaplasia, PanIN Development, and Fibrosis
por: Garcia-Carracedo, Dario, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_001hoe6jsojsthovsahfh6r0km