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Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders

Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant and a non-pro-vitamin A carotenoid. Lycopene has been found to be efficient in ameliorating cancer insurgences, diabetes mel...

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Autores principales: Imran, Muhammad, Ghorat, Fereshteh, Ul-Haq, Iahtisham, Ur-Rehman, Habib, Aslam, Farhan, Heydari, Mojtaba, Shariati, Mohammad Ali, Okuskhanova, Eleonora, Yessimbekov, Zhanibek, Thiruvengadam, Muthu, Hashempur, Mohammad Hashem, Rebezov, Maksim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464847/
https://www.ncbi.nlm.nih.gov/pubmed/32759751
http://dx.doi.org/10.3390/antiox9080706
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author Imran, Muhammad
Ghorat, Fereshteh
Ul-Haq, Iahtisham
Ur-Rehman, Habib
Aslam, Farhan
Heydari, Mojtaba
Shariati, Mohammad Ali
Okuskhanova, Eleonora
Yessimbekov, Zhanibek
Thiruvengadam, Muthu
Hashempur, Mohammad Hashem
Rebezov, Maksim
author_facet Imran, Muhammad
Ghorat, Fereshteh
Ul-Haq, Iahtisham
Ur-Rehman, Habib
Aslam, Farhan
Heydari, Mojtaba
Shariati, Mohammad Ali
Okuskhanova, Eleonora
Yessimbekov, Zhanibek
Thiruvengadam, Muthu
Hashempur, Mohammad Hashem
Rebezov, Maksim
author_sort Imran, Muhammad
collection PubMed
description Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant and a non-pro-vitamin A carotenoid. Lycopene has been found to be efficient in ameliorating cancer insurgences, diabetes mellitus, cardiac complications, oxidative stress-mediated malfunctions, inflammatory events, skin and bone diseases, hepatic, neural and reproductive disorders. This review summarizes information regarding its sources and uses amongst different societies, its biochemistry aspects, and the potential utilization of lycopene and possible mechanisms involved in alleviating the abovementioned disorders. Furthermore, future directions with the possible use of this nutraceutical against lifestyle-related disorders are emphasized. Its protective effects against recommended doses of toxic agents and toxicity and safety are also discussed.
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spelling pubmed-74648472020-09-04 Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders Imran, Muhammad Ghorat, Fereshteh Ul-Haq, Iahtisham Ur-Rehman, Habib Aslam, Farhan Heydari, Mojtaba Shariati, Mohammad Ali Okuskhanova, Eleonora Yessimbekov, Zhanibek Thiruvengadam, Muthu Hashempur, Mohammad Hashem Rebezov, Maksim Antioxidants (Basel) Review Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant and a non-pro-vitamin A carotenoid. Lycopene has been found to be efficient in ameliorating cancer insurgences, diabetes mellitus, cardiac complications, oxidative stress-mediated malfunctions, inflammatory events, skin and bone diseases, hepatic, neural and reproductive disorders. This review summarizes information regarding its sources and uses amongst different societies, its biochemistry aspects, and the potential utilization of lycopene and possible mechanisms involved in alleviating the abovementioned disorders. Furthermore, future directions with the possible use of this nutraceutical against lifestyle-related disorders are emphasized. Its protective effects against recommended doses of toxic agents and toxicity and safety are also discussed. MDPI 2020-08-04 /pmc/articles/PMC7464847/ /pubmed/32759751 http://dx.doi.org/10.3390/antiox9080706 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Imran, Muhammad
Ghorat, Fereshteh
Ul-Haq, Iahtisham
Ur-Rehman, Habib
Aslam, Farhan
Heydari, Mojtaba
Shariati, Mohammad Ali
Okuskhanova, Eleonora
Yessimbekov, Zhanibek
Thiruvengadam, Muthu
Hashempur, Mohammad Hashem
Rebezov, Maksim
Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
title Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
title_full Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
title_fullStr Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
title_full_unstemmed Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
title_short Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
title_sort lycopene as a natural antioxidant used to prevent human health disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464847/
https://www.ncbi.nlm.nih.gov/pubmed/32759751
http://dx.doi.org/10.3390/antiox9080706
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