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Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy

Rho-associated protein kinase (ROCK) inhibitors allow for causative glaucoma therapy. Unfortunately, topically applied ROCK inhibitors suffer from high incidence of hyperemia and low intraocular bioavailability. Therefore, we propose the use of poly (lactide-co-glycolide) (PLGA) microspheres as a de...

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Detalles Bibliográficos
Autores principales:	Mietzner, Raphael, Kade, Christian, Froemel, Franziska, Pauly, Diana, Stamer, W. Daniel, Ohlmann, Andreas, Wegener, Joachim, Fuchshofer, Rudolf, Breunig, Miriam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464914/ https://www.ncbi.nlm.nih.gov/pubmed/32727014 http://dx.doi.org/10.3390/pharmaceutics12080706

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