Cargando…

Ultra-Micro-Scale-Fractionation (UMSF) as a Powerful Tool for Bioactive Molecules Discovery

Herein is detailed the development and validation of an ultra-micro-scale-fractionation (UMSF) technique for the discovery of plant-based, bioactive molecules, coupling the advantages of ultra-performance liquid chromatography mass spectrometry (UPLC-MS) separations with microtiter plate-based bioas...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCallum, Jason L., Vacon, Jennifer N. D., Kirby, Christopher W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464926/ https://www.ncbi.nlm.nih.gov/pubmed/32806767 http://dx.doi.org/10.3390/molecules25163677

Ejemplares similares

Bioactive Molecules from Plants: Discovery and Pharmaceutical Applications
por: Bergonzi, Maria Camilla, et al.
Publicado: (2022)

Paramylon and Other Bioactive Molecules in Micro and Macroalgae
por: Barsanti, Laura, et al.
Publicado: (2022)

Drug discovery inspired by bioactive small molecules from nature
por: Kim, Seyun, et al.
Publicado: (2022)

The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination
por: Jones, Christopher G., et al.
Publicado: (2018)

An Ultra-Low-Power Embedded Processor with Variable Micro-Architecture
por: Ma, Wenheng, et al.
Publicado: (2021)

Second-Generation DNA-Templated Macrocycle Libraries for the Discovery of Bioactive Small Molecules
por: Usanov, Dmitry L., et al.
Publicado: (2018)

Lambda-Display: A Powerful Tool for Antigen Discovery
por: Beghetto, Elisa, et al.
Publicado: (2011)

Cryo-EM as a powerful tool for drug discovery
por: Van Drie, John H, et al.
Publicado: (2020)

Large-scale bioactivity analysis of the small-molecule assayed proteome
por: Backman, Tyler William H., et al.
Publicado: (2017)

Application of Ultra-Small Micro Grinding and Micro Milling Tools: Possibilities and Limitations
por: Kirsch, Benjamin, et al.
Publicado: (2017)

ChEMBL: a large-scale bioactivity database for drug discovery
por: Gaulton, Anna, et al.
Publicado: (2012)

Ultra-Scaled Si Nanowire Biosensors for Single DNA Molecule Detection †
por: Afzalian, Aryan, et al.
Publicado: (2023)

A Review of Computational Tools in microRNA Discovery
por: Gomes, Clarissa P. C., et al.
Publicado: (2013)

Micro-RNAs in Human Placenta: Tiny Molecules, Immense Power
por: Jin, Meiyuan, et al.
Publicado: (2022)

Sequence-based design of bioactive small molecules that target precursor microRNAs
por: Velagapudi, Sai Pradeep, et al.
Publicado: (2014)

Phytochemical Characterization of Wild Hops (Humulus lupulus ssp. lupuloides) Germplasm Resources From the Maritimes Region of Canada
por: McCallum, Jason L., et al.
Publicado: (2019)

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery
por: Ye, Ling F., et al.
Publicado: (2020)

Bottom-Up, On-Surface-Synthesized Armchair Graphene Nanoribbons for Ultra-High-Power Micro-Supercapacitors
por: Liu, Zhaoyang, et al.
Publicado: (2020)

Bioactive Molecules and Their Mechanisms of Action
por: Wang, Dongdong, et al.
Publicado: (2019)

PLATO: A Predictive Drug Discovery Web Platform for Efficient Target Fishing and Bioactivity Profiling of Small Molecules
por: Ciriaco, Fulvio, et al.
Publicado: (2022)

Bioinformatics approach: A powerful tool for microRNA research
por: Rasheed, Zafar
Publicado: (2017)

Bipolar Electrochemistry – A Powerful Tool for Micro/Nano‐Electrochemistry
por: Wang, Yu‐Ling, et al.
Publicado: (2022)

Optimizing the diagnostic power with gastric emptying scintigraphy at multiple time points
por: Hou, Qingjiang, et al.
Publicado: (2011)

Ultra low-power electronics and design
por: Macii, E
Publicado: (1988)

Fractionated Marine Invertebrate Extract Libraries for Drug Discovery
por: Bugni, Tim S., et al.
Publicado: (2008)

AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor
por: Ren, Feng, et al.
Publicado: (2023)

Margaritaria nobilis L.F. (Phyllanthaceae): Ethnopharmacology and Application of Computational Tools in the Annotation of Bioactive Molecules
por: Santiago, Johan Carlos C., et al.
Publicado: (2022)

Single Molecule FRET: A Powerful Tool to Study Intrinsically Disordered Proteins
por: LeBlanc, Sharonda J., et al.
Publicado: (2018)

Designing bioactive molecules : three dimensional techniques and applications
Publicado: (1998)

Untethered Magnetic Soft Robot with Ultra‐Flexible Wirelessly Rechargeable Micro‐Supercapacitor as an Onboard Power Source
por: Nardekar, Swapnil Shital, et al.
Publicado: (2023)

Ac/Ds-transposon activation tagging in poplar: a powerful tool for gene discovery
por: Fladung, Matthias, et al.
Publicado: (2012)

Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power?
por: Zuberi, Aamir, et al.
Publicado: (2016)

Corticospinal and Reticulospinal Contacts on Cervical Commissural and Long Descending Propriospinal Neurons in the Adult Rat Spinal Cord; Evidence for Powerful Reticulospinal Connections
por: Mitchell, Emma J., et al.
Publicado: (2016)

Combining enyne metathesis with long-established organic transformations: a powerful strategy for the sustainable synthesis of bioactive molecules
por: Dragutan, Valerian, et al.
Publicado: (2020)

Cynara cardunculus Crude Extract as a Powerful Natural Herbicide and Insight into the Mode of Action of Its Bioactive Molecules
por: Ben Kaab, Sofiene, et al.
Publicado: (2020)

Genome-Wide Association Study towards Genomic Predictive Power for High Production and Quality of Milk in American Alpine Goats
por: Tilahun, Y., et al.
Publicado: (2020)

Correction: Corticospinal and Reticulospinal Contacts on Cervical Commissural and Long Descending Propriospinal Neurons in the Adult Rat Spinal Cord; Evidence for Powerful Reticulospinal Connections
por: Mitchell, Emma J., et al.
Publicado: (2016)

Photocleavable linker for the patterning of bioactive molecules
por: Wegner, Seraphine V., et al.
Publicado: (2015)

Planctomycetes as Novel Source of Bioactive Molecules
por: Graça, Ana P., et al.
Publicado: (2016)

Bioactive Molecules from Extreme Environments
por: Giordano, Daniela
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_uj94t9l5gqb5dh9fqgs740c2mv