Micro-Clotting of Platelet-Rich Plasma Upon Loading in Hydrogel Microspheres Leads to Prolonged Protein Release and Slower Microsphere Degradation

Platelet-rich plasma (PRP) is an autologous blood product that contains a variety of growth factors (GFs) that are released upon platelet activation. Despite some therapeutic potential of PRP in vitro, in vivo data are not convincing. Bolus injection of PRP is cleared rapidly from the body diminishi...

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Detalles Bibliográficos
Autores principales: Choi, Miran Hannah, Blanco, Alexandra, Stealey, Samuel, Duan, Xin, Case, Natasha, Sell, Scott Allen, Rai, Muhammad Farooq, Zustiak, Silviya Petrova
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464943/
https://www.ncbi.nlm.nih.gov/pubmed/32751604
http://dx.doi.org/10.3390/polym12081712

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