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Electrosprayed Alginate Nanoparticles as CRISPR Plasmid DNA Delivery Carrier: Preparation, Optimization, and Characterization

Therapeutic gene editing is becoming more feasible with the emergence of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein (Cas) system. However, the successful implementation of CRISPR/Cas9-based therapeutics requires a safe and efficient in vivo deliv...

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Detalles Bibliográficos
Autores principales: Alallam, Batoul, Altahhan, Sara, Taher, Muhammad, Mohd Nasir, Mohd Hamzah, Doolaanea, Abd Almonem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465179/
https://www.ncbi.nlm.nih.gov/pubmed/32707857
http://dx.doi.org/10.3390/ph13080158