In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles

Macrophages are the front soldiers of the innate immune system and are vital for immune defense, tumor surveillance, and tissue homeostasis. In chronic diseases, including cancer and liver fibrosis, macrophages can be forced into an immunosuppressive and profibrotic M2 phenotype. M2-type macrophages...

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Detalles Bibliográficos
Autores principales: Kaps, Leonard, Leber, Nadine, Klefenz, Adrian, Choteschovsky, Niklas, Zentel, Rudolf, Nuhn, Lutz, Schuppan, Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465192/
https://www.ncbi.nlm.nih.gov/pubmed/32824208
http://dx.doi.org/10.3390/cells9081905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465192/
https://www.ncbi.nlm.nih.gov/pubmed/32824208
http://dx.doi.org/10.3390/cells9081905

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