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Amelioration of Congenital Tufting Enteropathy in EpCAM (TROP1)-Deficient Mice via Heterotopic Expression of TROP2 in Intestinal Epithelial Cells

TROP1 (EpCAM) and TROP2 are homologous cell surface proteins that are widely expressed, and often co-expressed, in developing and adult epithelia. Various functions have been ascribed to EpCAM and TROP2, but responsible mechanisms are incompletely characterized and functional equivalence has not bee...

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Detalles Bibliográficos
Autores principales: Nakato, Gaku, Morimura, Sohshi, Lu, Michael, Feng, Xu, Wu, Chuanjin, Udey, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465201/
https://www.ncbi.nlm.nih.gov/pubmed/32781650
http://dx.doi.org/10.3390/cells9081847