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Amelioration of Congenital Tufting Enteropathy in EpCAM (TROP1)-Deficient Mice via Heterotopic Expression of TROP2 in Intestinal Epithelial Cells
TROP1 (EpCAM) and TROP2 are homologous cell surface proteins that are widely expressed, and often co-expressed, in developing and adult epithelia. Various functions have been ascribed to EpCAM and TROP2, but responsible mechanisms are incompletely characterized and functional equivalence has not bee...
Autores principales: | Nakato, Gaku, Morimura, Sohshi, Lu, Michael, Feng, Xu, Wu, Chuanjin, Udey, Mark C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465201/ https://www.ncbi.nlm.nih.gov/pubmed/32781650 http://dx.doi.org/10.3390/cells9081847 |
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