Germline Genetic Findings Which May Impact Therapeutic Decisions in Families with a Presumed Predisposition for Hereditary Breast and Ovarian Cancer

In this study, we aim to gain insight in the germline mutation spectrum of ATM, BARD1, BRIP1, ERCC4, PALB2, RAD51C and RAD51D in breast and ovarian cancer families from Spain. We have selected 180 index cases in whom a germline mutation in BRCA1 and BRCA2 was previously ruled out. The importance of...

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Detalles Bibliográficos
Autores principales: Velázquez, Carolina, K., De Leeneer, Esteban-Cardeñosa, Eva M., Avila Cobos, Francisco, Lastra, Enrique, Abella, Luis E., de la Cruz, Virginia, Lobatón, Carmen D., Claes, Kathleen B., Durán, Mercedes, Infante, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465232/
https://www.ncbi.nlm.nih.gov/pubmed/32756499
http://dx.doi.org/10.3390/cancers12082151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465232/
https://www.ncbi.nlm.nih.gov/pubmed/32756499
http://dx.doi.org/10.3390/cancers12082151

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