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Sirt1-PPARS Cross-Talk in Complex Metabolic Diseases and Inherited Disorders of the One Carbon Metabolism

Sirtuin1 (Sirt1) has a NAD (+) binding domain and modulates the acetylation status of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC1α) and Fork Head Box O1 transcription factor (Foxo1) according to the nutritional status. Sirt1 is decreased in obese patients and increased in weigh...

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Detalles Bibliográficos
Autores principales:	Kosgei, Viola J., Coelho, David, Guéant-Rodriguez, Rosa-Maria, Guéant, Jean-Louis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465293/ https://www.ncbi.nlm.nih.gov/pubmed/32796716 http://dx.doi.org/10.3390/cells9081882

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