A novel antiviral lncRNA, EDAL, shields a T309 O-GlcNAcylation site to promote EZH2 lysosomal degradation

BACKGROUND: The central nervous system (CNS) is vulnerable to viral infection, yet few host factors in the CNS are known to defend against invasion by neurotropic viruses. Long noncoding RNAs (lncRNAs) have been revealed to play critical roles in a wide variety of biological processes and are highly...

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Detalles Bibliográficos
Autores principales: Sui, Baokun, Chen, Dong, Liu, Wei, Wu, Qiong, Tian, Bin, Li, Yingying, Hou, Jing, Liu, Shiyong, Xie, Juan, Jiang, Hao, Luo, Zhaochen, Lv, Lei, Huang, Fei, Li, Ruiming, Zhang, Chengguang, Tian, Yuling, Cui, Min, Zhou, Ming, Chen, Huanchun, Fu, Zhen F., Zhang, Yi, Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465408/
https://www.ncbi.nlm.nih.gov/pubmed/32873321
http://dx.doi.org/10.1186/s13059-020-02150-9

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