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The Effect of Particle Size and Surface Roughness of Spray-Dried Bosentan Microparticles on Aerodynamic Performance for Dry Powder Inhalation

The purpose of this study was to prepare spray dried bosentan microparticles for dry powder inhaler and to characterize its physicochemical and aerodynamic properties. The microparticles were prepared from ethanol/water solutions containing bosentan using spray dryer. Three types of formulations (SD...

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Detalles Bibliográficos
Autores principales:	Kwon, Yong-Bin, Kang, Ji-Hyun, Han, Chang-Soo, Kim, Dong-Wook, Park, Chun-Woong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465523/ https://www.ncbi.nlm.nih.gov/pubmed/32823545 http://dx.doi.org/10.3390/pharmaceutics12080765

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