Implications of a Change of Paradigm in Alpha1 Antitrypsin Deficiency Augmentation Therapy: From Biochemical to Clinical Efficacy

Ever since the first studies, restoring proteinase imbalance in the lung has traditionally been considered as the main goal of alpha1 antitrypsin (AAT) replacement therapy. This strategy was therefore based on ensuring biochemical efficacy, identifying a protection threshold, and evaluating differen...

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Detalles Bibliográficos
Autores principales: López-Campos, José Luis, Carrasco Hernandez, Laura, Caballero Eraso, Candelaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465600/
https://www.ncbi.nlm.nih.gov/pubmed/32764414
http://dx.doi.org/10.3390/jcm9082526

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