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pipeComp, a general framework for the evaluation of computational pipelines, reveals performant single cell RNA-seq preprocessing tools

We present pipeComp (https://github.com/plger/pipeComp), a flexible R framework for pipeline comparison handling interactions between analysis steps and relying on multi-level evaluation metrics. We apply it to the benchmark of single-cell RNA-sequencing analysis pipelines using simulated and real d...

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Detalles Bibliográficos
Autores principales:	Germain, Pierre-Luc, Sonrel, Anthony, Robinson, Mark D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465801/ https://www.ncbi.nlm.nih.gov/pubmed/32873325 http://dx.doi.org/10.1186/s13059-020-02136-7

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