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Aggressive Digital Papillary Adenocarcinoma Mimicking a Giant Cell Tumour – A Case Report and Review of the Literature

Aggressive digital papillary adenocarcinoma (ADPAca) is a rare, underreported, and often misdiagnosed malignant tumour of the eccrine sweat gland, with high recurrence and metastatic potential. We present a case of a painless mass over the middle phalanx of the dominant index finger in a 51-year-old...

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Autores principales: Joyce, Kenneth, Leonard, Niamh, Theopold, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465832/
https://www.ncbi.nlm.nih.gov/pubmed/32905077
http://dx.doi.org/10.7759/cureus.9531
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author Joyce, Kenneth
Leonard, Niamh
Theopold, Christoph
author_facet Joyce, Kenneth
Leonard, Niamh
Theopold, Christoph
author_sort Joyce, Kenneth
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description Aggressive digital papillary adenocarcinoma (ADPAca) is a rare, underreported, and often misdiagnosed malignant tumour of the eccrine sweat gland, with high recurrence and metastatic potential. We present a case of a painless mass over the middle phalanx of the dominant index finger in a 51-year-old man. The mass was present for over 20 years, which had slowly increased in size. The patient only presented when it began to interfere with his profession as an electrician. The clinical presentation was consistent with a giant cell tumour. Histological diagnosis was of an ADPAca. Staging investigations were negative and he subsequently went on to have a ray amputation. The importance of high clinical suspicion of digit lesions is highlighted. No specific histologic features have been identified to predict recurrence or metastasis. We review the merits of performing sentinel node biopsy and alternative treatment options such as Moh’s micrographic surgery. We review the international literature to assess metastatic potential and follow-up requirements.
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spelling pubmed-74658322020-09-03 Aggressive Digital Papillary Adenocarcinoma Mimicking a Giant Cell Tumour – A Case Report and Review of the Literature Joyce, Kenneth Leonard, Niamh Theopold, Christoph Cureus Dermatology Aggressive digital papillary adenocarcinoma (ADPAca) is a rare, underreported, and often misdiagnosed malignant tumour of the eccrine sweat gland, with high recurrence and metastatic potential. We present a case of a painless mass over the middle phalanx of the dominant index finger in a 51-year-old man. The mass was present for over 20 years, which had slowly increased in size. The patient only presented when it began to interfere with his profession as an electrician. The clinical presentation was consistent with a giant cell tumour. Histological diagnosis was of an ADPAca. Staging investigations were negative and he subsequently went on to have a ray amputation. The importance of high clinical suspicion of digit lesions is highlighted. No specific histologic features have been identified to predict recurrence or metastasis. We review the merits of performing sentinel node biopsy and alternative treatment options such as Moh’s micrographic surgery. We review the international literature to assess metastatic potential and follow-up requirements. Cureus 2020-08-03 /pmc/articles/PMC7465832/ /pubmed/32905077 http://dx.doi.org/10.7759/cureus.9531 Text en Copyright © 2020, Joyce et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Joyce, Kenneth
Leonard, Niamh
Theopold, Christoph
Aggressive Digital Papillary Adenocarcinoma Mimicking a Giant Cell Tumour – A Case Report and Review of the Literature
title Aggressive Digital Papillary Adenocarcinoma Mimicking a Giant Cell Tumour – A Case Report and Review of the Literature
title_full Aggressive Digital Papillary Adenocarcinoma Mimicking a Giant Cell Tumour – A Case Report and Review of the Literature
title_fullStr Aggressive Digital Papillary Adenocarcinoma Mimicking a Giant Cell Tumour – A Case Report and Review of the Literature
title_full_unstemmed Aggressive Digital Papillary Adenocarcinoma Mimicking a Giant Cell Tumour – A Case Report and Review of the Literature
title_short Aggressive Digital Papillary Adenocarcinoma Mimicking a Giant Cell Tumour – A Case Report and Review of the Literature
title_sort aggressive digital papillary adenocarcinoma mimicking a giant cell tumour – a case report and review of the literature
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465832/
https://www.ncbi.nlm.nih.gov/pubmed/32905077
http://dx.doi.org/10.7759/cureus.9531
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