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3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering

Fabrication of nerve conduits for perfectly repairing or replacing damaged peripheral nerve is an urgent demand worldwide, but it is also a formidable clinical challenge. In the last decade, with the rapid development of manufacture technologies, 3D printing and bioprinting have been becoming remark...

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Autores principales: Yu, Xiaoling, Zhang, Tian, Li, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465920/
https://www.ncbi.nlm.nih.gov/pubmed/32717878
http://dx.doi.org/10.3390/polym12081637
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author Yu, Xiaoling
Zhang, Tian
Li, Yuan
author_facet Yu, Xiaoling
Zhang, Tian
Li, Yuan
author_sort Yu, Xiaoling
collection PubMed
description Fabrication of nerve conduits for perfectly repairing or replacing damaged peripheral nerve is an urgent demand worldwide, but it is also a formidable clinical challenge. In the last decade, with the rapid development of manufacture technologies, 3D printing and bioprinting have been becoming remarkable stars in the field of neural engineering. In this review, we explore that the biomaterial inks (hydrogels, thermoplastic, and thermoset polyesters and composite) and bioinks have been selected for 3D printing and bioprinting of peripheral nerve conduits. This review covers 3D manufacturing technologies, including extrusion printing, inkjet printing, stereolithography, and bioprinting with inclusion of cells, bioactive molecules, and drugs. Finally, an outlook on the future directions of 3D printing and 4D printing in customizable nerve therapies is presented.
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spelling pubmed-74659202020-09-04 3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering Yu, Xiaoling Zhang, Tian Li, Yuan Polymers (Basel) Review Fabrication of nerve conduits for perfectly repairing or replacing damaged peripheral nerve is an urgent demand worldwide, but it is also a formidable clinical challenge. In the last decade, with the rapid development of manufacture technologies, 3D printing and bioprinting have been becoming remarkable stars in the field of neural engineering. In this review, we explore that the biomaterial inks (hydrogels, thermoplastic, and thermoset polyesters and composite) and bioinks have been selected for 3D printing and bioprinting of peripheral nerve conduits. This review covers 3D manufacturing technologies, including extrusion printing, inkjet printing, stereolithography, and bioprinting with inclusion of cells, bioactive molecules, and drugs. Finally, an outlook on the future directions of 3D printing and 4D printing in customizable nerve therapies is presented. MDPI 2020-07-23 /pmc/articles/PMC7465920/ /pubmed/32717878 http://dx.doi.org/10.3390/polym12081637 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yu, Xiaoling
Zhang, Tian
Li, Yuan
3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering
title 3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering
title_full 3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering
title_fullStr 3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering
title_full_unstemmed 3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering
title_short 3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering
title_sort 3d printing and bioprinting nerve conduits for neural tissue engineering
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465920/
https://www.ncbi.nlm.nih.gov/pubmed/32717878
http://dx.doi.org/10.3390/polym12081637
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