Prevention of Venous Thromboembolism in 2020 and Beyond

Venous thromboembolism (VTE) is the third most common cause of vascular mortality worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In this review, we discuss how an understanding of VTE epidemiology and the results of thromboprophylaxis trials have shaped the current a...

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Autores principales: Nicholson, Matthew, Chan, Noel, Bhagirath, Vinai, Ginsberg, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465935/
https://www.ncbi.nlm.nih.gov/pubmed/32752154
http://dx.doi.org/10.3390/jcm9082467
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author Nicholson, Matthew
Chan, Noel
Bhagirath, Vinai
Ginsberg, Jeffrey
author_facet Nicholson, Matthew
Chan, Noel
Bhagirath, Vinai
Ginsberg, Jeffrey
author_sort Nicholson, Matthew
collection PubMed
description Venous thromboembolism (VTE) is the third most common cause of vascular mortality worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In this review, we discuss how an understanding of VTE epidemiology and the results of thromboprophylaxis trials have shaped the current approach to VTE prevention. We will discuss modern thromboprophylaxis as it pertains to genetic risk factors, exogenous hormonal therapies, pregnancy, surgery, medical hospitalization, cancer, and what is known thus far about VTE in COVID-19 infection.
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spelling pubmed-74659352020-09-04 Prevention of Venous Thromboembolism in 2020 and Beyond Nicholson, Matthew Chan, Noel Bhagirath, Vinai Ginsberg, Jeffrey J Clin Med Review Venous thromboembolism (VTE) is the third most common cause of vascular mortality worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In this review, we discuss how an understanding of VTE epidemiology and the results of thromboprophylaxis trials have shaped the current approach to VTE prevention. We will discuss modern thromboprophylaxis as it pertains to genetic risk factors, exogenous hormonal therapies, pregnancy, surgery, medical hospitalization, cancer, and what is known thus far about VTE in COVID-19 infection. MDPI 2020-08-01 /pmc/articles/PMC7465935/ /pubmed/32752154 http://dx.doi.org/10.3390/jcm9082467 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nicholson, Matthew
Chan, Noel
Bhagirath, Vinai
Ginsberg, Jeffrey
Prevention of Venous Thromboembolism in 2020 and Beyond
title Prevention of Venous Thromboembolism in 2020 and Beyond
title_full Prevention of Venous Thromboembolism in 2020 and Beyond
title_fullStr Prevention of Venous Thromboembolism in 2020 and Beyond
title_full_unstemmed Prevention of Venous Thromboembolism in 2020 and Beyond
title_short Prevention of Venous Thromboembolism in 2020 and Beyond
title_sort prevention of venous thromboembolism in 2020 and beyond
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465935/
https://www.ncbi.nlm.nih.gov/pubmed/32752154
http://dx.doi.org/10.3390/jcm9082467
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