Therapeutic Target Discovery Using High-Throughput Genetic Screens in Acute Myeloid Leukemia

The development of high-throughput gene manipulating tools such as short hairpin RNA (shRNA) and CRISPR/Cas9 libraries has enabled robust characterization of novel functional genes contributing to the pathological states of the diseases. In acute myeloid leukemia (AML), these genetic screen approach...

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Detalles Bibliográficos
Autores principales: Liu, Qiao, Garcia, Michelle, Wang, Shaoyuan, Chen, Chun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465943/
https://www.ncbi.nlm.nih.gov/pubmed/32806592
http://dx.doi.org/10.3390/cells9081888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465943/
https://www.ncbi.nlm.nih.gov/pubmed/32806592
http://dx.doi.org/10.3390/cells9081888

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