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Therapeutic Target Discovery Using High-Throughput Genetic Screens in Acute Myeloid Leukemia

The development of high-throughput gene manipulating tools such as short hairpin RNA (shRNA) and CRISPR/Cas9 libraries has enabled robust characterization of novel functional genes contributing to the pathological states of the diseases. In acute myeloid leukemia (AML), these genetic screen approach...

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Detalles Bibliográficos
Autores principales:	Liu, Qiao, Garcia, Michelle, Wang, Shaoyuan, Chen, Chun-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465943/ https://www.ncbi.nlm.nih.gov/pubmed/32806592 http://dx.doi.org/10.3390/cells9081888

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