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Pathological Consequences of Hepatic mTORC1 Dysregulation
The mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of metabolism that integrates environmental inputs, including nutrients, growth factors, and stress signals. mTORC1 activation upregulates anabolism of diverse macromolecules, such as proteins, lipids, and nucleic acids, whi...
Autores principales: | Cho, Chun-Seok, Kowalsky, Allison Ho, Lee, Jun Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465966/ https://www.ncbi.nlm.nih.gov/pubmed/32764389 http://dx.doi.org/10.3390/genes11080896 |
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