Cargando…

Infection and Activation of B Cells by Theiler’s Murine Encephalomyelitis Virus (TMEV) Leads to Autoantibody Production in an Infectious Model of Multiple Sclerosis

Theiler’s murine encephalomyelitis virus (TMEV) induces immune-mediated inflammatory demyelinating disease in susceptible mice that is similar to human multiple sclerosis (MS). In light of anti-CD20 therapies for MS, the susceptibility of B cells to TMEV infection is particularly important. In our s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Young-Hee, Kim, Charles X., Huang, Jocelin, Kim, Byung S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465974/ https://www.ncbi.nlm.nih.gov/pubmed/32727036 http://dx.doi.org/10.3390/cells9081787

Ejemplares similares

Leader (L) and L* proteins of Theiler's murine encephalomyelitis virus (TMEV) and their regulation of the virus' biological activities
por: Takano-Maruyama, Masumi, et al.
Publicado: (2006)

Host genetic diversity drives variable central nervous system lesion distribution in chronic phase of Theiler’s Murine Encephalomyelitis Virus (TMEV) infection
por: Lawley, Koedi S., et al.
Publicado: (2021)

Pathogenesis of Theiler's Murine Encephalomyelitis Virus
por: Yamada, Masahito, et al.
Publicado: (1991)

Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease(): III. Failure of neuroantigen-specific immune tolerance to affect the clinical course of demyelination
por: Miller, Stephen D., et al.
Publicado: (1990)

Innate immune response induced by Theiler's murine encephalomyelitis virus infection
por: Kim, Byung S., et al.
Publicado: (2005)

Characterization of Ribosomal Frameshifting in Theiler's Murine Encephalomyelitis Virus
por: Finch, Leanne K., et al.
Publicado: (2015)

Theiler's Murine Encephalomyelitis Virus as a Vaccine Candidate for Immunotherapy
por: Pavelko, Kevin D., et al.
Publicado: (2011)

TDP-43 proteinopathy in Theiler’s murine encephalomyelitis virus infection
por: Masaki, Katsuhisa, et al.
Publicado: (2019)

Facets of Theiler’s Murine Encephalomyelitis Virus-Induced Diseases: An Update
por: Gerhauser, Ingo, et al.
Publicado: (2019)

Nitric Oxide in TMEV
por: Oleszak, Emilia L., et al.
Publicado: (2005)

Comparison of Reported Spinal Cord Lesions in Progressive Multiple Sclerosis with Theiler’s Murine Encephalomyelitis Virus Induced Demyelinating Disease
por: Leitzen, Eva, et al.
Publicado: (2019)

Gut dysbiosis and neuroimmune responses to brain infection with Theiler’s murine encephalomyelitis virus
por: Carrillo-Salinas, F. J., et al.
Publicado: (2017)

Cannabidiol reduces seizures following CNS infection with Theiler's murine encephalomyelitis virus
por: Patel, Dipan C., et al.
Publicado: (2019)

Characterization of the stimulators of protein-directed ribosomal frameshifting in Theiler's murine encephalomyelitis virus
por: Napthine, Sawsan, et al.
Publicado: (2019)

Theiler’s virus-induced demyelinating disease as an infectious model of progressive multiple sclerosis
por: Pike, Steven C., et al.
Publicado: (2022)

TMEV and Neuroantigens: Myelin Genes and Proteins, Molecular Mimicry, Epitope Spreading, and Autoantibody-Mediated Remyelination
por: Tsunoda, Ikuo, et al.
Publicado: (2005)

Theiler’s murine encephalomyelitis virus attachment to the gastrointestinal tract is associated with sialic acid binding
por: Tsunoda, Ikuo, et al.
Publicado: (2009)

Astrocyte depletion alters extracellular matrix composition in the demyelinating phase of Theiler’s murine encephalomyelitis
por: Allnoch, Lisa, et al.
Publicado: (2022)

Effect of teriflunomide on cortex-basal ganglia-thalamus (CxBGTh) circuit glutamatergic dysregulation in the Theiler's Murine Encephalomyelitis Virus mouse model of multiple sclerosis
por: Modica, Claire M., et al.
Publicado: (2017)

Modulation of viral replication in macrophages persistently infected with the DA strain of Theiler's murine encephalomyelitis virus
por: Steurbaut, Stephane, et al.
Publicado: (2008)

Reactive Oxygen Species Are Key Mediators of Demyelination in Canine Distemper Leukoencephalitis but not in Theiler’s Murine Encephalomyelitis
por: Attig, Friederike, et al.
Publicado: (2019)

Screening of prototype antiseizure and anti‐inflammatory compounds in the Theiler's murine encephalomyelitis virus model of epilepsy
por: Metcalf, Cameron S., et al.
Publicado: (2021)

Monoclonal antibody to Theiler's murine encephalomyelitis virus defines a determinant on myelin and oligodendrocytes, and augments demyelination in experimental allergic encephalomyelitis
Publicado: (1990)

Theiler’s murine encephalomyelitis virus infection of astrocytes induces the expression of chemokines which attract activated but not resting T lymphocytes
por: Rubio, Nazario, et al.
Publicado: (2019)

Differential transcription of matrix-metalloproteinase genes in primary mouse astrocytes and microglia infected with Theiler’s murine encephalomyelitis virus
por: Kumnok, Jirawat, et al.
Publicado: (2008)

Effect of Siponimod on Brain and Spinal Cord Imaging Markers of Neurodegeneration in the Theiler’s Murine Encephalomyelitis Virus Model of Demyelination
por: Pol, Suyog, et al.
Publicado: (2023)

Alteration of amino acid 101 within capsid protein VP-1 changes the pathogenicity of Theiler's murine encephalomyelitis virus
Publicado: (1989)

Comparison of Theiler’s Murine Encephalomyelitis Virus Induced Spinal Cord and Peripheral Nerve Lesions Following Intracerebral and Intraspinal Infection
por: Jin, Wen, et al.
Publicado: (2019)

Reactivity and increased proliferation of NG2 cells following central nervous system infection with Theiler’s murine encephalomyelitis virus
por: Bell, Laura A., et al.
Publicado: (2020)

Ovalbumin-specific CD4(+) and CD8(+) T cells contribute to different susceptibility for Theiler’s murine encephalomyelitis virus persistence
por: Wannemacher, Rouven, et al.
Publicado: (2023)

RELATION OF IRON SALTS TO INHIBITION OF GLYCOLYSIS BY THEILER FA VIRUS OF MOUSE ENCEPHALOMYELITIS
por: Racker, E., et al.
Publicado: (1947)

Development of a duplex real-time RT-PCR for the simultaneous detection and differentiation of Theiler’s murine encephalomyelitis virus and rat theilovirus
por: Yuan, Wen, et al.
Publicado: (2016)

Gut metabolite S‐equol ameliorates hyperexcitability in entorhinal cortex neurons following Theiler murine encephalomyelitis virus‐induced acute seizures
por: Gallucci, Allison, et al.
Publicado: (2021)

IFNAR signaling of neuroectodermal cells is essential for the survival of C57BL/6 mice infected with Theiler’s murine encephalomyelitis virus
por: Bühler, Melanie, et al.
Publicado: (2023)

Viral models of multiple sclerosis: Neurodegeneration and demyelination in mice infected with Theiler's virus
por: Mecha, Miriam, et al.
Publicado: (2013)

Immune mechanisms of Theiler's virus-induced demyelination
por: Kim, Byung Suk, et al.
Publicado: (1999)

Vacuolar neuronal degeneration in the ventral horns of SCID mice in naturally occurring Theiler's encephalomyelitis
por: Rozengurt, Nora, et al.
Publicado: (1992)

Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler’s Murine Encephalomyelitis
por: Hansmann, Florian, et al.
Publicado: (2019)

IFN-β Deficiency Results in Fatal or Demyelinating Disease in C57BL/6 Mice Infected With Theiler’s Murine Encephalomyelitis Viruses
por: Bühler, Melanie, et al.
Publicado: (2022)

Viral Clearance and Neuroinflammation in Acute TMEV Infection Vary by Host Genetic Background
por: Lawley, Koedi S., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fvngvafr6hm4224umrpmtsseo2