Nuclear Accumulation of LAP1:TRF2 Complex during DNA Damage Response Uncovers a Novel Role for LAP1

Lamina-associated polypeptide 1 (LAP1) is a nuclear envelope (NE) protein whose function remains poorly characterized. In a recent LAP1 protein interactome study, a putative regulatory role in the DNA damage response (DDR) has emerged and telomeric repeat-binding factor 2 (TRF2), a protein intimatel...

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Detalles Bibliográficos
Autores principales: Pereira, Cátia D., Martins, Filipa, Santos, Mariana, Müeller, Thorsten, da Cruz e Silva, Odete A. B., Rebelo, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465990/
https://www.ncbi.nlm.nih.gov/pubmed/32751253
http://dx.doi.org/10.3390/cells9081804

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