Cargando…

Metabolic Profiling Reveals Significant Perturbations of Intracellular Glucose Homeostasis in Enterovirus-Infected Cells

Enterovirus A71 (EV-A71) is a common cause of hand, foot, and mouth disease. Severe EV-A71 infections may be associated with life-threatening neurological complications. However, the pathogenic mechanisms underlying these severe clinical and pathological features remain incompletely understood. Meta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zou, Zijiao, Tsang, Jessica Oi-Ling, Yan, Bingpeng, Chik, Kenn Ka-Heng, Chan, Chris Chun-Yiu, Cao, Jianli, Liang, Ronghui, Tang, Kaiming, Yin, Feifei, Ye, Zi-Wei, Chu, Hin, Chan, Jasper Fuk-Woo, Yuan, Shuofeng, Yuen, Kwok-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466099/ https://www.ncbi.nlm.nih.gov/pubmed/32717953 http://dx.doi.org/10.3390/metabo10080302

Ejemplares similares

Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells
por: Yan, Bingpeng, et al.
Publicado: (2019)

1899. The Cellular Kinase Inhibitor OSU-03012 Inhibits Enterovirus 71 In Vitro
por: Chan, Jasper, et al.
Publicado: (2018)

Vemurafenib Inhibits Enterovirus A71 Genome Replication and Virus Assembly
por: Hu, Bodan, et al.
Publicado: (2022)

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)
por: Yuan, Shuofeng, et al.
Publicado: (2020)

In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor
por: Wen, Lei, et al.
Publicado: (2021)

Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses
por: Tsang, Jessica Oi-Ling, et al.
Publicado: (2021)

Severe fever with thrombocytopenia syndrome virus (SFTSV)-host interactome screen identifies viral nucleoprotein-associated host factors as potential antiviral targets
por: Cao, Jianli, et al.
Publicado: (2021)

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2018)

Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus
por: Yuan, Shuofeng, et al.
Publicado: (2019)

Phosphatidic acid phosphatase 1 impairs SARS-CoV-2 replication by affecting the glycerophospholipid metabolism pathway
por: Yan, Bingpeng, et al.
Publicado: (2022)

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy
por: Zhu, Zheng, et al.
Publicado: (2019)

2642. Development of Human Intestinal Organoids as an Antiviral Evaluation Platform for Enteroviruses
por: Fuk-Woo Chan, Jasper, et al.
Publicado: (2019)

SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
por: Qiao, Wei, et al.
Publicado: (2022)

Author Correction: SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
por: Qiao, Wei, et al.
Publicado: (2022)

hnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs
por: Zhang, Xi, et al.
Publicado: (2022)

Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system
por: Yuan, Shuofeng, et al.
Publicado: (2020)

SARS-CoV-2 exploits host DGAT and ADRP for efficient replication
por: Yuan, Shuofeng, et al.
Publicado: (2021)

Targeting papain-like protease for broad-spectrum coronavirus inhibition
por: Yuan, Shuofeng, et al.
Publicado: (2022)

918. Identification of novel druggable host targets for Middle East respiratory syndrome coronavirus using a quantitative phosphoproteomics approach
por: Chan, Jasper F W, et al.
Publicado: (2023)

The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage
por: Liang, Ronghui, et al.
Publicado: (2022)

Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication
por: Yan, Bingpeng, et al.
Publicado: (2019)

Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection
por: Ye, Zi-Wei, et al.
Publicado: (2021)

Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant
por: Xia, Shuai, et al.
Publicado: (2022)

Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus
por: Zhao, Xiaoyu, et al.
Publicado: (2021)

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2020)

Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2016)

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters
por: Lee, Andrew Chak-Yiu, et al.
Publicado: (2020)

A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters
por: Zhang, Bao-Zhong, et al.
Publicado: (2021)

Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis
por: Zhou, Jie, et al.
Publicado: (2015)

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study
por: Chu, Hin, et al.
Publicado: (2020)

Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation
por: Zhang, Xi, et al.
Publicado: (2020)

STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells
por: Yang, Dong, et al.
Publicado: (2021)

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters
por: Zhang, Anna Jinxia, et al.
Publicado: (2020)

A pan-sarbecovirus vaccine induces highly potent and durable neutralizing antibody responses in non-human primates against SARS-CoV-2 Omicron variant
por: Liu, Zezhong, et al.
Publicado: (2022)

Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2016)

Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies
por: Zhou, Dongyan, et al.
Publicado: (2021)

A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge
por: Zhou, Biao, et al.
Publicado: (2022)

Cellular Sensors and Viral Countermeasures: A Molecular Arms Race between Host and SARS-CoV-2
por: Sun, Haoran, et al.
Publicado: (2023)

Orally administered bismuth drug together with N-acetyl cysteine as a broad-spectrum anti-coronavirus cocktail therapy
por: Wang, Runming, et al.
Publicado: (2021)

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target
por: Yuan, Shuofeng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j24f84l6laem29gm0l4ao63c1v