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Heart Failure is Highly Prevalent and Difficult to Diagnose in Severe Exacerbations of COPD Presenting to the Emergency Department

Background: Some 20% of patients with stable Chronic Obstructive Pulmonary Disease (COPD) might have heart failure (HF). HF contribution to acute exacerbations of COPD (AECOPD) presenting to the emergency department (ED) is not well established. Aims: To assess (1) the HF incidence in patients prese...

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Autores principales: Tinè, Mariaenrica, Bazzan, Erica, Semenzato, Umberto, Biondini, Davide, Cocconcelli, Elisabetta, Balestro, Elisabetta, Casara, Alvise, Baraldo, Simonetta, Turato, Graziella, Cosio, Manuel G., Saetta, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466112/
https://www.ncbi.nlm.nih.gov/pubmed/32823938
http://dx.doi.org/10.3390/jcm9082644
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author Tinè, Mariaenrica
Bazzan, Erica
Semenzato, Umberto
Biondini, Davide
Cocconcelli, Elisabetta
Balestro, Elisabetta
Casara, Alvise
Baraldo, Simonetta
Turato, Graziella
Cosio, Manuel G.
Saetta, Marina
author_facet Tinè, Mariaenrica
Bazzan, Erica
Semenzato, Umberto
Biondini, Davide
Cocconcelli, Elisabetta
Balestro, Elisabetta
Casara, Alvise
Baraldo, Simonetta
Turato, Graziella
Cosio, Manuel G.
Saetta, Marina
author_sort Tinè, Mariaenrica
collection PubMed
description Background: Some 20% of patients with stable Chronic Obstructive Pulmonary Disease (COPD) might have heart failure (HF). HF contribution to acute exacerbations of COPD (AECOPD) presenting to the emergency department (ED) is not well established. Aims: To assess (1) the HF incidence in patients presenting to the ED with AECOPD; (2) the concordance between ED and respiratory ward (RW) diagnosis; (3) the factors associated with risk of death after hospital discharge. Methods: Retrospective chart review of 119 COPD patients presenting to ED for acute exacerbation of respiratory symptoms and then admitted to RW where a final diagnosis of AECOPD, AECOPD and HF and AECOPD and OD (other diagnosis), was obtained. ED and RW diagnosis were then compared. Factors affecting survival at follow-up were investigated. Results: At RW, 40.3% of cases were diagnosed of AECOPD, 40.3% of AECOPD and HF and 19.4% of AECOPD and OD, with ED diagnosis coinciding with RW’s in 67%, 23%, and 57% of cases respectively. At RW, 60% of patients in GOLD1 had HF, of which 43% were diagnosed at ED, while 40% in GOLD4 had HF that was never diagnosed at ED. Lack of inclusion in a COPD care program, HF, and early readmission for AECOPD were associated with mortality. Conclusions: HF is highly prevalent and difficult to diagnose in patients in all GOLD stages presenting to the ED with severe AECOPD, and along with lack of inclusion in a COPD care program, confers a high risk for mortality.
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spelling pubmed-74661122020-09-14 Heart Failure is Highly Prevalent and Difficult to Diagnose in Severe Exacerbations of COPD Presenting to the Emergency Department Tinè, Mariaenrica Bazzan, Erica Semenzato, Umberto Biondini, Davide Cocconcelli, Elisabetta Balestro, Elisabetta Casara, Alvise Baraldo, Simonetta Turato, Graziella Cosio, Manuel G. Saetta, Marina J Clin Med Article Background: Some 20% of patients with stable Chronic Obstructive Pulmonary Disease (COPD) might have heart failure (HF). HF contribution to acute exacerbations of COPD (AECOPD) presenting to the emergency department (ED) is not well established. Aims: To assess (1) the HF incidence in patients presenting to the ED with AECOPD; (2) the concordance between ED and respiratory ward (RW) diagnosis; (3) the factors associated with risk of death after hospital discharge. Methods: Retrospective chart review of 119 COPD patients presenting to ED for acute exacerbation of respiratory symptoms and then admitted to RW where a final diagnosis of AECOPD, AECOPD and HF and AECOPD and OD (other diagnosis), was obtained. ED and RW diagnosis were then compared. Factors affecting survival at follow-up were investigated. Results: At RW, 40.3% of cases were diagnosed of AECOPD, 40.3% of AECOPD and HF and 19.4% of AECOPD and OD, with ED diagnosis coinciding with RW’s in 67%, 23%, and 57% of cases respectively. At RW, 60% of patients in GOLD1 had HF, of which 43% were diagnosed at ED, while 40% in GOLD4 had HF that was never diagnosed at ED. Lack of inclusion in a COPD care program, HF, and early readmission for AECOPD were associated with mortality. Conclusions: HF is highly prevalent and difficult to diagnose in patients in all GOLD stages presenting to the ED with severe AECOPD, and along with lack of inclusion in a COPD care program, confers a high risk for mortality. MDPI 2020-08-14 /pmc/articles/PMC7466112/ /pubmed/32823938 http://dx.doi.org/10.3390/jcm9082644 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tinè, Mariaenrica
Bazzan, Erica
Semenzato, Umberto
Biondini, Davide
Cocconcelli, Elisabetta
Balestro, Elisabetta
Casara, Alvise
Baraldo, Simonetta
Turato, Graziella
Cosio, Manuel G.
Saetta, Marina
Heart Failure is Highly Prevalent and Difficult to Diagnose in Severe Exacerbations of COPD Presenting to the Emergency Department
title Heart Failure is Highly Prevalent and Difficult to Diagnose in Severe Exacerbations of COPD Presenting to the Emergency Department
title_full Heart Failure is Highly Prevalent and Difficult to Diagnose in Severe Exacerbations of COPD Presenting to the Emergency Department
title_fullStr Heart Failure is Highly Prevalent and Difficult to Diagnose in Severe Exacerbations of COPD Presenting to the Emergency Department
title_full_unstemmed Heart Failure is Highly Prevalent and Difficult to Diagnose in Severe Exacerbations of COPD Presenting to the Emergency Department
title_short Heart Failure is Highly Prevalent and Difficult to Diagnose in Severe Exacerbations of COPD Presenting to the Emergency Department
title_sort heart failure is highly prevalent and difficult to diagnose in severe exacerbations of copd presenting to the emergency department
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466112/
https://www.ncbi.nlm.nih.gov/pubmed/32823938
http://dx.doi.org/10.3390/jcm9082644
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