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Exosomes-Mediated Transfer of Itga2 Promotes Migration and Invasion of Prostate Cancer Cells by Inducing Epithelial-Mesenchymal Transition

Although integrin alpha 2 subunit (ITGA2) mediates cancer progression and metastasis, its transfer by exosomes has not been investigated in prostate cancer (PCa). We aimed to determine the role of exosomal ITGA2 derived from castration-resistant PCa (CRPC) cells in promoting aggressive phenotypes in...

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Detalles Bibliográficos
Autores principales: Gaballa, Rofaida, Ali, Hamdy E. A., Mahmoud, Mohamed O., Rhim, Johng S., Ali, Hamed I., Salem, Heba F., Saleem, Mohammad, Kandeil, Mohamed A., Ambs, Stefan, Abd Elmageed, Zakaria Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466113/
https://www.ncbi.nlm.nih.gov/pubmed/32824235
http://dx.doi.org/10.3390/cancers12082300