The Value of Targeting Complement Components in Asthma

Asthma is an important respiratory illness. Though pharmacological and biological treatment is well established and is staged according to endotypes and their responses to treatment, novel avenues are being explored. Our focus is complement. In this viewpoint, we evaluate the approach to target comp...

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Detalles Bibliográficos
Autores principales: Mohamed, Marwa M. E., Nicklin, Alicia D., Stover, Cordula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466339/
https://www.ncbi.nlm.nih.gov/pubmed/32806638
http://dx.doi.org/10.3390/medicina56080405
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author Mohamed, Marwa M. E.
Nicklin, Alicia D.
Stover, Cordula M.
author_facet Mohamed, Marwa M. E.
Nicklin, Alicia D.
Stover, Cordula M.
author_sort Mohamed, Marwa M. E.
collection PubMed
description Asthma is an important respiratory illness. Though pharmacological and biological treatment is well established and is staged according to endotypes and their responses to treatment, novel avenues are being explored. Our focus is complement. In this viewpoint, we evaluate the approach to target complement in this complex hypersensitivity reaction that develops chronicity and has a personal—as well as a societal—cost.
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spelling pubmed-74663392020-09-14 The Value of Targeting Complement Components in Asthma Mohamed, Marwa M. E. Nicklin, Alicia D. Stover, Cordula M. Medicina (Kaunas) Perspective Asthma is an important respiratory illness. Though pharmacological and biological treatment is well established and is staged according to endotypes and their responses to treatment, novel avenues are being explored. Our focus is complement. In this viewpoint, we evaluate the approach to target complement in this complex hypersensitivity reaction that develops chronicity and has a personal—as well as a societal—cost. MDPI 2020-08-12 /pmc/articles/PMC7466339/ /pubmed/32806638 http://dx.doi.org/10.3390/medicina56080405 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Mohamed, Marwa M. E.
Nicklin, Alicia D.
Stover, Cordula M.
The Value of Targeting Complement Components in Asthma
title The Value of Targeting Complement Components in Asthma
title_full The Value of Targeting Complement Components in Asthma
title_fullStr The Value of Targeting Complement Components in Asthma
title_full_unstemmed The Value of Targeting Complement Components in Asthma
title_short The Value of Targeting Complement Components in Asthma
title_sort value of targeting complement components in asthma
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466339/
https://www.ncbi.nlm.nih.gov/pubmed/32806638
http://dx.doi.org/10.3390/medicina56080405
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