Cargando…

EphA2-enriched exosomes promote cell migration and are a potential diagnostic serum marker in pancreatic cancer

Pancreatic cancer (PC) is the fourth most common cause of cancer-related mortality worldwide and is characterized by high invasiveness and early metastasis. To identify novel diagnostic markers, the present study aimed to understand the mechanism underlying PC progression. The present study demonstr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Qian, Wei, Lijuan, Zhang, Jingya, Li, Ze, Feng, Honglei, Ren, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466360/ https://www.ncbi.nlm.nih.gov/pubmed/32945400 http://dx.doi.org/10.3892/mmr.2020.11384

Ejemplares similares

Serum Exosomal EphA2 is a Prognostic Biomarker in Patients with Pancreatic Cancer
por: Wei, Qian, et al.
Publicado: (2021)

Chemoresistance Transmission via Exosome-Mediated EphA2 Transfer in Pancreatic Cancer
por: Fan, Jia, et al.
Publicado: (2018)

EphA5 and EphA6: regulation of neuronal and spine morphology
por: Das, Gitanjali, et al.
Publicado: (2016)

Ephrin Receptors (Eph): EphA1, EphA5, and EphA7 Expression in Uveal Melanoma—Associations with Clinical Parameters and Patient Survival
por: Gajdzis, Malgorzata, et al.
Publicado: (2020)

EphA8 is a prognostic marker for epithelial ovarian cancer
por: Liu, Xiaoqin, et al.
Publicado: (2016)

Vaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumors
por: Hatano, Manabu, et al.
Publicado: (2004)

Development of an In-House EphA2 ELISA for Human Serum and Measurement of Circulating Levels of EphA2 in Hypertensive Patients with Renal Dysfunction
por: Murakoshi, Maki, et al.
Publicado: (2022)

Exosomal MicroRNA-10a Is Associated with Liver Regeneration in Rats through Downregulation of EphA4
por: Luo, Lin, et al.
Publicado: (2018)

Targeting EphA2 in cancer
por: Xiao, Ta, et al.
Publicado: (2020)

The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size
por: Zapata-Mercado, Elmer, et al.
Publicado: (2022)

Drug-resistant cancer cell-derived exosomal EphA2 promotes breast cancer metastasis via the EphA2-Ephrin A1 reverse signaling
por: Gao, Zicong, et al.
Publicado: (2021)

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia
por: Charmsaz, Sara, et al.
Publicado: (2015)

Roles of EphA2 in Development and Disease
por: Park, Jeong Eun, et al.
Publicado: (2013)

The EphA1 and EphA2 Signaling Modulates the Epithelial Permeability in Human Sinonasal Epithelial Cells and the Rhinovirus Infection Induces Epithelial Barrier Dysfunction via EphA2 Receptor Signaling
por: Shin, Jae Min, et al.
Publicado: (2023)

Y772 phosphorylation of EphA2 is responsible for EphA2-dependent NPC nasopharyngeal carcinoma growth by Shp2/Erk-1/2 signaling pathway
por: Xiang, Yi-Ping, et al.
Publicado: (2020)

Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine
por: Quinn, Bridget A., et al.
Publicado: (2016)

Therapeutic Targeting of Pancreatic Cancer via EphA2 Dimeric Agonistic Agents
por: Salem, Ahmed F., et al.
Publicado: (2020)

Downregulation of EphA5 by promoter methylation in human prostate cancer
por: Li, Shibao, et al.
Publicado: (2015)

EphA2 Proteolytic Fragment as a Sensitive Diagnostic Biomarker for Very Early-stage Pancreatic Ductal Carcinoma
por: Sato, Shinya, et al.
Publicado: (2023)

EphA2 bears plasticity to tumor invasion
por: Sugiyama, Nami, et al.
Publicado: (2013)

Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model
por: Bhatia, Shilpa, et al.
Publicado: (2015)

Protein kinase A can block EphA2 receptor–mediated cell repulsion by increasing EphA2 S897 phosphorylation
por: Barquilla, Antonio, et al.
Publicado: (2016)

EphA5 protein, a potential marker for distinguishing histological grade and prognosis in ovarian serous carcinoma
por: Chen, Xiao, et al.
Publicado: (2016)

A Novel Occulta-Type Spina Bifida Mediated by Murine Double Heterozygotes EphA2 and EphA4 Receptor Tyrosine Kinases
por: Abdullah, Nor Linda, et al.
Publicado: (2017)

EphA2 and EGFR: Friends in Life, Partners in Crime. Can EphA2 Be a Predictive Biomarker of Response to Anti-EGFR Agents?
por: Cioce, Mario, et al.
Publicado: (2021)

Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing
por: Volta, Francesco, et al.
Publicado: (2019)

EphA3 Functions are Regulated by Collaborating Phosphotyrosine Residues
por: Shi, Guanfang, et al.
Publicado: (2010)

EphA4 is a prognostic factor in gastric cancer
por: Miyazaki, Kohji, et al.
Publicado: (2013)

Unliganded EphA3 dimerization promoted by the SAM domain
por: Singh, Deo R., et al.
Publicado: (2015)

Identification and characterization of Nanobodies targeting the EphA4 receptor
por: Schoonaert, Lies, et al.
Publicado: (2017)

Oncogenic Functions and Therapeutic Targeting of EphA2 in Cancer
por: Wilson, Kalin, et al.
Publicado: (2021)

Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration
por: Peng, Jing, et al.
Publicado: (2021)

The role of EphA2 in ADAM17- and ionizing radiation-enhanced lung cancer cell migration
por: Waller, Verena, et al.
Publicado: (2023)

Differential Roles for EphA and EphB Signaling in Segregation and Patterning of Central Vestibulocochlear Nerve Projections
por: Allen-Sharpley, Michelle R., et al.
Publicado: (2013)

Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery
por: Stammes, Marieke A., et al.
Publicado: (2017)

Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer
por: Chang, Q, et al.
Publicado: (2008)

Specific detection of soluble EphA2 fragments in blood as a new biomarker for pancreatic cancer
por: Koshikawa, Naohiko, et al.
Publicado: (2017)

EphA2 super-enhancer promotes tumor progression by recruiting FOSL2 and TCF7L2 to activate the target gene EphA2
por: Cui, Shuang, et al.
Publicado: (2021)

Novel [(111)In]In-BnDTPA-EphA2-230-1 Antibody for Single-Photon Emission Computed Tomography Imaging Tracer Targeting of EphA2
por: Furukawa, Takenori, et al.
Publicado: (2023)

The Diagnostic Significance of PDGF, EphA7, CCR5, and CCL5 Levels in Colorectal Cancer
por: Üçüncü, Muhammed, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1ujkbhsulimsdnv7jqsjjm05dt