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Superparamagnetic Iron Oxide Nanoparticles Carrying Chemotherapeutics Improve Drug Efficacy in Monolayer and Spheroid Cell Culture by Enabling Active Accumulation

Cytotoxic and cytostatic chemotherapeutics act by attacking rapidly dividing tumor cells, predominantly affecting malignant tissue and to a certain degree preserving healthy cells. Nonetheless, severe side effects are caused as quickly proliferating healthy cells such as hematopoietic precursors and...

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Detalles Bibliográficos
Autores principales: Nguyen, Khanh, Nuß, Bianca, Mühlberger, Marina, Unterweger, Harald, Friedrich, Ralf P., Alexiou, Christoph, Janko, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466387/
https://www.ncbi.nlm.nih.gov/pubmed/32796757
http://dx.doi.org/10.3390/nano10081577