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Superparamagnetic Iron Oxide Nanoparticles Carrying Chemotherapeutics Improve Drug Efficacy in Monolayer and Spheroid Cell Culture by Enabling Active Accumulation
Cytotoxic and cytostatic chemotherapeutics act by attacking rapidly dividing tumor cells, predominantly affecting malignant tissue and to a certain degree preserving healthy cells. Nonetheless, severe side effects are caused as quickly proliferating healthy cells such as hematopoietic precursors and...
Autores principales: | Nguyen, Khanh, Nuß, Bianca, Mühlberger, Marina, Unterweger, Harald, Friedrich, Ralf P., Alexiou, Christoph, Janko, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466387/ https://www.ncbi.nlm.nih.gov/pubmed/32796757 http://dx.doi.org/10.3390/nano10081577 |
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