Cargando…
Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer
BACKGROUND: Cisplatin is a first-line drug for the treatment of human non-small cell lung cancer (NSCLC); however, the majority of patients will develop drug resistance after treatment. In order to overcome cisplatin resistance, it is important to understand the mechanisms underlying the resistance....
Autores principales: | Wang, Wenjing, Zhao, Mengyue, Cui, Lijuan, Ren, Yong, Zhang, Jingyuan, Chen, Junli, Jia, Lina, Zhang, Jiayu, Yang, Jingyu, Chen, Guoliang, Ashby, Charles R., Wu, Chunfu, Chen, Zhe-Sheng, Wang, Lihui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466461/ https://www.ncbi.nlm.nih.gov/pubmed/32878625 http://dx.doi.org/10.1186/s12943-020-01256-9 |
Ejemplares similares
-
The function of bacterial HtrA is evolutionally conserved in mammalian HtrA2/Omi
por: Chung, Hea-Jong, et al.
Publicado: (2020) -
Activity-Modulating Monoclonal Antibodies to the Human Serine Protease HtrA3 Provide Novel Insights into Regulating HtrA Proteolytic Activities
por: Singh, Harmeet, et al.
Publicado: (2014) -
The Novel Role of HtrA1 in Gingivitis, Chronic and Aggressive Periodontitis
por: Lorenzi, Teresa, et al.
Publicado: (2014) -
Targeting HDAC/OAZ1 axis with a novel inhibitor effectively reverses cisplatin resistance in non-small cell lung cancer
por: Sun, Yuhong, et al.
Publicado: (2019) -
HtrA1: Its future potential as a novel biomarker for cancer
por: ALTOBELLI, EMMA, et al.
Publicado: (2015)