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Determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single Centre observational study

BACKGROUND: Recent studies show that substantial percentage of patients experienced worsening of health related quality of life (HRQoL) 1 year after cardiac surgery. The aim of this study is to identify risk factors that interfere with improvement of HRQoL. METHODS: From December 2015 till July 2017...

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Autores principales: Rijnhart-de Jong, Hilda, Haenen, Jo, Bol Raap, Goris, Jekel, Lilian, Vossenberg, Tessel, Bondarenko, Olga, Boerma, Christiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466488/
https://www.ncbi.nlm.nih.gov/pubmed/32873336
http://dx.doi.org/10.1186/s13019-020-01273-1
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author Rijnhart-de Jong, Hilda
Haenen, Jo
Bol Raap, Goris
Jekel, Lilian
Vossenberg, Tessel
Bondarenko, Olga
Boerma, Christiaan
author_facet Rijnhart-de Jong, Hilda
Haenen, Jo
Bol Raap, Goris
Jekel, Lilian
Vossenberg, Tessel
Bondarenko, Olga
Boerma, Christiaan
author_sort Rijnhart-de Jong, Hilda
collection PubMed
description BACKGROUND: Recent studies show that substantial percentage of patients experienced worsening of health related quality of life (HRQoL) 1 year after cardiac surgery. The aim of this study is to identify risk factors that interfere with improvement of HRQoL. METHODS: From December 2015 till July 2017 a prospective single centre observational study was carried out in 1920 patients participated who underwent non-salvage cardiac surgery. All patients were requested to complete a Short Form 36 (SF-36) questionnaire before and 1 year after surgery. Primary aim of the study was to identify risk factors for non-recovery in the physical domain of the SF-36 in all cardiac surgery patients. Secondary aim was to identify identical risk factors in patients with isolated coronary artery bypass grafting. RESULTS: After cardiac surgery, the questionnaires for physical and mental health were completed by respectively 803 and 807 patients. Median age was 69[62–75] years, and 77% was male. In comparison to the preoperative status, 176 patients (21.9%) did not display an improvement in the SF-36 physical domain score 1 year after cardiac surgery. In a multivariate analysis independent risk factors for non-recovery in the SF-36 physical domain were baseline SF36 physical domain score (OR 0.954[0.942–0.965], P < 0.001), diabetes (OR 0.437 [0.265–0.720], P 0.001), female sex (OR 0.492 [0.307–0.789], P 0.003), post-operative infection (OR 0.240 [0.109–0.525], P < 0.001) and PCI within 1 year (OR 0.113 [0.036–0.349], P < 0.001) For isolated CABG, 23.2% of patients did not display an improvement in the physical domain score and risk factors appeared to be identical. CONCLUSIONS: Twenty two percent of all cardiac surgery patients did not show an improvement in the physical domain score of the HRQoL between the preoperative period and 1 year after surgery. Independent risk factors for non-recovery after cardiac surgery were baseline SF-36 physical domain score, diabetes, female sex, any postoperative infection and the need for PCI in the first year. Further research is needed to tailor the patient selection procedure prior to surgery and potentially modify risk factors in the perioperative process. TRIAL REGISTRATION: Due to type of study not applicable. https://www.ccmo.nl/metcs/erkende-metcs/regionale-toetsingscommissie-patientgebonden-onderzoek.
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spelling pubmed-74664882020-09-03 Determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single Centre observational study Rijnhart-de Jong, Hilda Haenen, Jo Bol Raap, Goris Jekel, Lilian Vossenberg, Tessel Bondarenko, Olga Boerma, Christiaan J Cardiothorac Surg Research Article BACKGROUND: Recent studies show that substantial percentage of patients experienced worsening of health related quality of life (HRQoL) 1 year after cardiac surgery. The aim of this study is to identify risk factors that interfere with improvement of HRQoL. METHODS: From December 2015 till July 2017 a prospective single centre observational study was carried out in 1920 patients participated who underwent non-salvage cardiac surgery. All patients were requested to complete a Short Form 36 (SF-36) questionnaire before and 1 year after surgery. Primary aim of the study was to identify risk factors for non-recovery in the physical domain of the SF-36 in all cardiac surgery patients. Secondary aim was to identify identical risk factors in patients with isolated coronary artery bypass grafting. RESULTS: After cardiac surgery, the questionnaires for physical and mental health were completed by respectively 803 and 807 patients. Median age was 69[62–75] years, and 77% was male. In comparison to the preoperative status, 176 patients (21.9%) did not display an improvement in the SF-36 physical domain score 1 year after cardiac surgery. In a multivariate analysis independent risk factors for non-recovery in the SF-36 physical domain were baseline SF36 physical domain score (OR 0.954[0.942–0.965], P < 0.001), diabetes (OR 0.437 [0.265–0.720], P 0.001), female sex (OR 0.492 [0.307–0.789], P 0.003), post-operative infection (OR 0.240 [0.109–0.525], P < 0.001) and PCI within 1 year (OR 0.113 [0.036–0.349], P < 0.001) For isolated CABG, 23.2% of patients did not display an improvement in the physical domain score and risk factors appeared to be identical. CONCLUSIONS: Twenty two percent of all cardiac surgery patients did not show an improvement in the physical domain score of the HRQoL between the preoperative period and 1 year after surgery. Independent risk factors for non-recovery after cardiac surgery were baseline SF-36 physical domain score, diabetes, female sex, any postoperative infection and the need for PCI in the first year. Further research is needed to tailor the patient selection procedure prior to surgery and potentially modify risk factors in the perioperative process. TRIAL REGISTRATION: Due to type of study not applicable. https://www.ccmo.nl/metcs/erkende-metcs/regionale-toetsingscommissie-patientgebonden-onderzoek. BioMed Central 2020-09-01 /pmc/articles/PMC7466488/ /pubmed/32873336 http://dx.doi.org/10.1186/s13019-020-01273-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Rijnhart-de Jong, Hilda
Haenen, Jo
Bol Raap, Goris
Jekel, Lilian
Vossenberg, Tessel
Bondarenko, Olga
Boerma, Christiaan
Determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single Centre observational study
title Determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single Centre observational study
title_full Determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single Centre observational study
title_fullStr Determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single Centre observational study
title_full_unstemmed Determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single Centre observational study
title_short Determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single Centre observational study
title_sort determinants of non-recovery in physical health-related quality of life one year after cardiac surgery: a prospective single centre observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466488/
https://www.ncbi.nlm.nih.gov/pubmed/32873336
http://dx.doi.org/10.1186/s13019-020-01273-1
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