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Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)
OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466494/ https://www.ncbi.nlm.nih.gov/pubmed/32873327 http://dx.doi.org/10.1186/s13104-020-05252-6 |
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author | Thim, Troels Götberg, Matthias Fröbert, Ole Nijveldt, Robin van Royen, Niels Baptista, Sergio Bravo Koul, Sasha Kellerth, Thomas Bøtker, Hans Erik Terkelsen, Christian Juhl Christiansen, Evald Høj Jakobsen, Lars Kristensen, Steen Dalby Maeng, Michael |
author_facet | Thim, Troels Götberg, Matthias Fröbert, Ole Nijveldt, Robin van Royen, Niels Baptista, Sergio Bravo Koul, Sasha Kellerth, Thomas Bøtker, Hans Erik Terkelsen, Christian Juhl Christiansen, Evald Høj Jakobsen, Lars Kristensen, Steen Dalby Maeng, Michael |
author_sort | Thim, Troels |
collection | PubMed |
description | OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5–32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR. |
format | Online Article Text |
id | pubmed-7466494 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-74664942020-09-03 Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy) Thim, Troels Götberg, Matthias Fröbert, Ole Nijveldt, Robin van Royen, Niels Baptista, Sergio Bravo Koul, Sasha Kellerth, Thomas Bøtker, Hans Erik Terkelsen, Christian Juhl Christiansen, Evald Høj Jakobsen, Lars Kristensen, Steen Dalby Maeng, Michael BMC Res Notes Research Note OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5–32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR. BioMed Central 2020-09-01 /pmc/articles/PMC7466494/ /pubmed/32873327 http://dx.doi.org/10.1186/s13104-020-05252-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Note Thim, Troels Götberg, Matthias Fröbert, Ole Nijveldt, Robin van Royen, Niels Baptista, Sergio Bravo Koul, Sasha Kellerth, Thomas Bøtker, Hans Erik Terkelsen, Christian Juhl Christiansen, Evald Høj Jakobsen, Lars Kristensen, Steen Dalby Maeng, Michael Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy) |
title | Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy) |
title_full | Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy) |
title_fullStr | Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy) |
title_full_unstemmed | Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy) |
title_short | Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy) |
title_sort | agreement between nonculprit stenosis follow-up ifr and ffr after stemi (istemi substudy) |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466494/ https://www.ncbi.nlm.nih.gov/pubmed/32873327 http://dx.doi.org/10.1186/s13104-020-05252-6 |
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