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Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)

OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow...

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Autores principales: Thim, Troels, Götberg, Matthias, Fröbert, Ole, Nijveldt, Robin, van Royen, Niels, Baptista, Sergio Bravo, Koul, Sasha, Kellerth, Thomas, Bøtker, Hans Erik, Terkelsen, Christian Juhl, Christiansen, Evald Høj, Jakobsen, Lars, Kristensen, Steen Dalby, Maeng, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466494/
https://www.ncbi.nlm.nih.gov/pubmed/32873327
http://dx.doi.org/10.1186/s13104-020-05252-6
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author Thim, Troels
Götberg, Matthias
Fröbert, Ole
Nijveldt, Robin
van Royen, Niels
Baptista, Sergio Bravo
Koul, Sasha
Kellerth, Thomas
Bøtker, Hans Erik
Terkelsen, Christian Juhl
Christiansen, Evald Høj
Jakobsen, Lars
Kristensen, Steen Dalby
Maeng, Michael
author_facet Thim, Troels
Götberg, Matthias
Fröbert, Ole
Nijveldt, Robin
van Royen, Niels
Baptista, Sergio Bravo
Koul, Sasha
Kellerth, Thomas
Bøtker, Hans Erik
Terkelsen, Christian Juhl
Christiansen, Evald Høj
Jakobsen, Lars
Kristensen, Steen Dalby
Maeng, Michael
author_sort Thim, Troels
collection PubMed
description OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5–32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR.
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spelling pubmed-74664942020-09-03 Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy) Thim, Troels Götberg, Matthias Fröbert, Ole Nijveldt, Robin van Royen, Niels Baptista, Sergio Bravo Koul, Sasha Kellerth, Thomas Bøtker, Hans Erik Terkelsen, Christian Juhl Christiansen, Evald Høj Jakobsen, Lars Kristensen, Steen Dalby Maeng, Michael BMC Res Notes Research Note OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5–32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR. BioMed Central 2020-09-01 /pmc/articles/PMC7466494/ /pubmed/32873327 http://dx.doi.org/10.1186/s13104-020-05252-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Thim, Troels
Götberg, Matthias
Fröbert, Ole
Nijveldt, Robin
van Royen, Niels
Baptista, Sergio Bravo
Koul, Sasha
Kellerth, Thomas
Bøtker, Hans Erik
Terkelsen, Christian Juhl
Christiansen, Evald Høj
Jakobsen, Lars
Kristensen, Steen Dalby
Maeng, Michael
Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)
title Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)
title_full Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)
title_fullStr Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)
title_full_unstemmed Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)
title_short Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)
title_sort agreement between nonculprit stenosis follow-up ifr and ffr after stemi (istemi substudy)
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466494/
https://www.ncbi.nlm.nih.gov/pubmed/32873327
http://dx.doi.org/10.1186/s13104-020-05252-6
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