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PPARγ Transcription Deficiency Exacerbates High-Fat Diet-Induced Adipocyte Hypertrophy and Insulin Resistance in Mice

BACKGROUND: The transcriptional factor peroxisome proliferator–activated receptor γ (PPARγ) is an important therapeutic target for the treatment of type 2 diabetes. However, the role of the PPARγ transcriptional activity remains ambiguous in its metabolic regulation. METHODS: Based on the crystal st...

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Detalles Bibliográficos
Autores principales:	Guo, Fusheng, Xu, Shuangshuang, Zhu, Yanlin, Zheng, Xing, Lu, Yi, Tu, Jui, He, Ying, Jin, Lihua, Li, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466717/ https://www.ncbi.nlm.nih.gov/pubmed/32973516 http://dx.doi.org/10.3389/fphar.2020.01285

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