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Multiscale Modeling of Cardiovascular Function Predicts That the End-Systolic Pressure Volume Relationship Can Be Targeted via Multiple Therapeutic Strategies

Most patients who develop heart failure are unable to elevate their cardiac output on demand due to impaired contractility and/or reduced ventricular filling. Despite decades of research, few effective therapies for heart failure have been developed. In part, this may reflect the difficulty of predi...

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Detalles Bibliográficos
Autores principales:	Campbell, Kenneth S., Chrisman, Brianna Sierra, Campbell, Stuart G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466769/ https://www.ncbi.nlm.nih.gov/pubmed/32973561 http://dx.doi.org/10.3389/fphys.2020.01043

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