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Dioscin Attenuates Interleukin 1β (IL-1β)-Induced Catabolism and Apoptosis via Modulating the Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-κB) Signaling in Human Nucleus Pulposus Cells

BACKGROUND: Nucleus pulposus (NP) cell dysfunction and apoptosis contribute to disc degeneration. Dioscin, a natural steroid saponin, has been demonstrated to have anti-inflammatory, antiapoptotic, and antioxidative effects in various diseases. However, little is known about the roles of dioscin in...

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Detalles Bibliográficos
Autores principales:	Wang, Longhui, Gu, Yuntao, Zhao, Hai, Chen, Rong, Chen, Wensheng, Qi, Hao, Gao, Weisong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2020
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466834/ https://www.ncbi.nlm.nih.gov/pubmed/32841225 http://dx.doi.org/10.12659/MSM.923386

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