The consensus immunoscore: toward a new classification of colorectal cancer

In its latest edition, the WHO classification of the Digestive System Tumors introduced for the first time the immune response as essential and desirable diagnostic criteria for colorectal cancer. The immune response within the tumor microenvironment is therefore clinically relevant. The consensus I...

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Detalles Bibliográficos
Autores principales: Lanzi, Anastasia, Pagès, Franck, Lagorce-Pagès, Christine, Galon, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466865/
https://www.ncbi.nlm.nih.gov/pubmed/32934885
http://dx.doi.org/10.1080/2162402X.2020.1789032
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author Lanzi, Anastasia
Pagès, Franck
Lagorce-Pagès, Christine
Galon, Jérôme
author_facet Lanzi, Anastasia
Pagès, Franck
Lagorce-Pagès, Christine
Galon, Jérôme
author_sort Lanzi, Anastasia
collection PubMed
description In its latest edition, the WHO classification of the Digestive System Tumors introduced for the first time the immune response as essential and desirable diagnostic criteria for colorectal cancer. The immune response within the tumor microenvironment is therefore clinically relevant. The consensus Immunoscore has a prognostic value that has been confirmed in a meta-analysis on more than 10,000 patients, and it provides a reliable estimate of the recurrence risk in colon cancer. The international validation of the prognostic value of the consensus Immunoscore for time to recurrence, disease-free survival and overall survival in colon cancer together with its predictive value of response to chemotherapy provides valuable information for patient care management.
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spelling pubmed-74668652020-09-14 The consensus immunoscore: toward a new classification of colorectal cancer Lanzi, Anastasia Pagès, Franck Lagorce-Pagès, Christine Galon, Jérôme Oncoimmunology Author's View In its latest edition, the WHO classification of the Digestive System Tumors introduced for the first time the immune response as essential and desirable diagnostic criteria for colorectal cancer. The immune response within the tumor microenvironment is therefore clinically relevant. The consensus Immunoscore has a prognostic value that has been confirmed in a meta-analysis on more than 10,000 patients, and it provides a reliable estimate of the recurrence risk in colon cancer. The international validation of the prognostic value of the consensus Immunoscore for time to recurrence, disease-free survival and overall survival in colon cancer together with its predictive value of response to chemotherapy provides valuable information for patient care management. Taylor & Francis 2020-07-11 /pmc/articles/PMC7466865/ /pubmed/32934885 http://dx.doi.org/10.1080/2162402X.2020.1789032 Text en © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Author's View
Lanzi, Anastasia
Pagès, Franck
Lagorce-Pagès, Christine
Galon, Jérôme
The consensus immunoscore: toward a new classification of colorectal cancer
title The consensus immunoscore: toward a new classification of colorectal cancer
title_full The consensus immunoscore: toward a new classification of colorectal cancer
title_fullStr The consensus immunoscore: toward a new classification of colorectal cancer
title_full_unstemmed The consensus immunoscore: toward a new classification of colorectal cancer
title_short The consensus immunoscore: toward a new classification of colorectal cancer
title_sort consensus immunoscore: toward a new classification of colorectal cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466865/
https://www.ncbi.nlm.nih.gov/pubmed/32934885
http://dx.doi.org/10.1080/2162402X.2020.1789032
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