Low Base-Substitution Mutation Rate but High Rate of Slippage Mutations in the Sequence Repeat-Rich Genome of Dictyostelium discoideum

We describe the rate and spectrum of spontaneous mutations for the social amoeba Dictyostelium discoideum, a key model organism in molecular, cellular, evolutionary and developmental biology. Whole-genome sequencing of 37 mutation accumulation lines of D. discoideum after an average of 1,500 cell di...

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Detalles Bibliográficos
Autores principales: Kucukyildirim, Sibel, Behringer, Megan, Sung, Way, Brock, Debra A., Doak, Thomas G., Mergen, Hatice, Queller, David C., Strassmann, Joan E., Lynch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466956/
https://www.ncbi.nlm.nih.gov/pubmed/32732307
http://dx.doi.org/10.1534/g3.120.401578

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