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The Impact of DNA Methylation Dynamics on the Mutation Rate During Human Germline Development

DNA methylation is a dynamic epigenetic modification found in most eukaryotic genomes. It is known to lead to a high CpG to TpG mutation rate. However, the relationship between the methylation dynamics in germline development and the germline mutation rate remains unexplored. In this study, we used...

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Detalles Bibliográficos
Autores principales:	Zhou, Yijia, He, Funan, Pu, Weilin, Gu, Xun, Wang, Jiucun, Su, Zhixi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2020
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466984/ https://www.ncbi.nlm.nih.gov/pubmed/32727923 http://dx.doi.org/10.1534/g3.120.401511

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