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Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019

The novel coronavirus 2019 (COVID‐19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented healthcare crisis. SARS‐CoV‐2 gets access into the human body mainly through the nose and the mouth and invades these mucosae in its destination to the...

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Autores principales: Abdulrab, S., Alkadasi, B., Al-maweri, S., Halboub, E., Alhadainy, H., Geerts, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467061/
https://www.ncbi.nlm.nih.gov/pubmed/32895614
http://dx.doi.org/10.1016/j.nmni.2020.100751
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author Abdulrab, S.
Alkadasi, B.
Al-maweri, S.
Halboub, E.
Alhadainy, H.
Geerts, G.
author_facet Abdulrab, S.
Alkadasi, B.
Al-maweri, S.
Halboub, E.
Alhadainy, H.
Geerts, G.
author_sort Abdulrab, S.
collection PubMed
description The novel coronavirus 2019 (COVID‐19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented healthcare crisis. SARS‐CoV‐2 gets access into the human body mainly through the nose and the mouth and invades these mucosae in its destination to the pulmonary tissues. Thus, the oral and nasal mucosae serve as the main routes and reservoirs for aerosolized transmission of the viral particles to the external environment and hence infection transmission. Statins have been shown to have antimicrobial, antiviral, antifungal, anti‐inflammatory, immunomodulatory, and antioxidant properties. Therefore, we hypothesize that using statins-based prophylactic mouthwashes will reduce COVID‐19 transmission in dental settings.
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spelling pubmed-74670612020-09-03 Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019 Abdulrab, S. Alkadasi, B. Al-maweri, S. Halboub, E. Alhadainy, H. Geerts, G. New Microbes New Infect Letter to the Editor The novel coronavirus 2019 (COVID‐19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented healthcare crisis. SARS‐CoV‐2 gets access into the human body mainly through the nose and the mouth and invades these mucosae in its destination to the pulmonary tissues. Thus, the oral and nasal mucosae serve as the main routes and reservoirs for aerosolized transmission of the viral particles to the external environment and hence infection transmission. Statins have been shown to have antimicrobial, antiviral, antifungal, anti‐inflammatory, immunomodulatory, and antioxidant properties. Therefore, we hypothesize that using statins-based prophylactic mouthwashes will reduce COVID‐19 transmission in dental settings. Elsevier 2020-09-02 /pmc/articles/PMC7467061/ /pubmed/32895614 http://dx.doi.org/10.1016/j.nmni.2020.100751 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Letter to the Editor
Abdulrab, S.
Alkadasi, B.
Al-maweri, S.
Halboub, E.
Alhadainy, H.
Geerts, G.
Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019
title Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019
title_full Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019
title_fullStr Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019
title_full_unstemmed Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019
title_short Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019
title_sort statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467061/
https://www.ncbi.nlm.nih.gov/pubmed/32895614
http://dx.doi.org/10.1016/j.nmni.2020.100751
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