Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity

Some imprinted genes exhibit parental origin specific expression bias rather than being transcribed exclusively from one copy. The physiological relevance of this remains poorly understood. In an analysis of brain-specific allele-biased expression, we identified that Trappc9, a cellular trafficking...

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Detalles Bibliográficos
Autores principales: Liang, Zhengzheng S., Cimino, Irene, Yalcin, Binnaz, Raghupathy, Narayanan, Vancollie, Valerie E., Ibarra-Soria, Ximena, Firth, Helen V., Rimmington, Debra, Farooqi, I. Sadaf, Lelliott, Christopher J., Munger, Steven C., O’Rahilly, Stephen, Ferguson-Smith, Anne C., Coll, Anthony P., Logan, Darren W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467316/
https://www.ncbi.nlm.nih.gov/pubmed/32877400
http://dx.doi.org/10.1371/journal.pgen.1008916

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