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CTLA-4 immunotherapy exposes differences in immune response along with different tumor progression in colorectal cancer

Tumor growth is accompanied by a changing tumor microenvironment and mutations that increase the resistance to therapy. Here, we used syngeneic models to evaluate the drug response of tumors of the same type of different sizes. We used the in vivo efficacy and Ki-67 immunohistochemistry (IHC) assay...

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Detalles Bibliográficos
Autores principales: Fu, Xiaocong, Luo, Hua, Zheng, Yuhui, Wang, Shengpeng, Zhong, Zhangfeng, Wang, Yitao, Yang, Yeguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467381/
https://www.ncbi.nlm.nih.gov/pubmed/32805718
http://dx.doi.org/10.18632/aging.103765