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Neutrophil depletion enhances the therapeutic effect of PD-1 antibody on glioma

Tumor-infiltrating neutrophils (TINs), the predominant leukocytes in the tumor microenvironment, are important for cancer-related immunosuppression. Combinations of multiple immune checkpoint inhibitors can significantly improve outcomes in murine glioma models. Here, we investigated TIN levels in h...

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Detalles Bibliográficos
Autores principales: Wang, Peng-Fei, Zhang, Yu-Xiang, Su, Jing, Yao, Kun, Li, Shou-Wei, Huang, Guang-Rui, Yan, Chang-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467393/
https://www.ncbi.nlm.nih.gov/pubmed/32756015
http://dx.doi.org/10.18632/aging.103428