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The Promise for Histone Methyltransferase Inhibitors for Epigenetic Therapy in Clinical Oncology: A Narrative Review
Epigenetic processes are essential for normal development and the maintenance of tissue-specific gene expression in mammals. Changes in gene expression and malignant cellular transformation can result from disruption of epigenetic mechanisms, and global disruption in the epigenetic landscape is a ke...
Autores principales: | Rugo, Hope S., Jacobs, Ira, Sharma, Shikhar, Scappaticci, Frank, Paul, Thomas A., Jensen-Pergakes, Kristen, Malouf, Gabriel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467409/ https://www.ncbi.nlm.nih.gov/pubmed/32445185 http://dx.doi.org/10.1007/s12325-020-01379-x |
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