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Implementation of a Reference-Scaled Average Bioequivalence Approach for Highly Variable Acetylsalicylic Acid in Fixed-Dose Combination with Clopidogrel Versus Enteric Aspirin in Chinese Subjects Under Fasting Conditions: A Phase 1, Open-Label, Randomized, Crossover Study

INTRODUCTION: Dual antiplatelet therapy, aspirin and a P2Y(12) inhibitor, is recommended to prevent thrombotic complications of acute coronary syndrome. Clopidogrel plus acetylsalicylic acid combination is the most commonly used dual antiplatelet therapy recommended by international guidelines and i...

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Detalles Bibliográficos
Autores principales:	Wang, Lu, Di, Yujing, Guo, Tingting, Ming, Jeffrey E., Kong, Fangyuan, Yin, Huiqiu, Zhang, Linlin, Xie, Fang, Yang, Na, Ping, Chuan, Li, Yi, Hou, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467447/ https://www.ncbi.nlm.nih.gov/pubmed/32418143 http://dx.doi.org/10.1007/s12325-020-01369-z

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