Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options

Intracranial atherosclerotic stenoses (ICAS) are one of the most common causes of first and recurrent cerebrovascular ischaemic events worldwide, with highest prevalence in Asian, Hispanic and African populations. Clinical trials have improved the understanding of epidemiology, risk factors and imag...

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Autores principales: Krasteva, Marina Petrova, Lau, Kui Kai, Mordasini, Pasquale, Tsang, Anderson Chun On, Heldner, Mirjam Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467483/
https://www.ncbi.nlm.nih.gov/pubmed/32270364
http://dx.doi.org/10.1007/s12325-020-01291-4
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author Krasteva, Marina Petrova
Lau, Kui Kai
Mordasini, Pasquale
Tsang, Anderson Chun On
Heldner, Mirjam Rachel
author_facet Krasteva, Marina Petrova
Lau, Kui Kai
Mordasini, Pasquale
Tsang, Anderson Chun On
Heldner, Mirjam Rachel
author_sort Krasteva, Marina Petrova
collection PubMed
description Intracranial atherosclerotic stenoses (ICAS) are one of the most common causes of first and recurrent cerebrovascular ischaemic events worldwide, with highest prevalence in Asian, Hispanic and African populations. Clinical trials have improved the understanding of epidemiology, risk factors and imaging characteristics of patients with ICAS. Current therapeutic approaches concerning these patients include management of risk factors, best medical therapy, potentially endovascular and rarely surgical therapy. In our review, we elucidate the current epidemiology and evidence in evaluation of risk factors and therapeutic options for providing favourable outcome for patients with ICAS.
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spelling pubmed-74674832020-09-11 Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options Krasteva, Marina Petrova Lau, Kui Kai Mordasini, Pasquale Tsang, Anderson Chun On Heldner, Mirjam Rachel Adv Ther Review Intracranial atherosclerotic stenoses (ICAS) are one of the most common causes of first and recurrent cerebrovascular ischaemic events worldwide, with highest prevalence in Asian, Hispanic and African populations. Clinical trials have improved the understanding of epidemiology, risk factors and imaging characteristics of patients with ICAS. Current therapeutic approaches concerning these patients include management of risk factors, best medical therapy, potentially endovascular and rarely surgical therapy. In our review, we elucidate the current epidemiology and evidence in evaluation of risk factors and therapeutic options for providing favourable outcome for patients with ICAS. Springer Healthcare 2020-04-08 2020 /pmc/articles/PMC7467483/ /pubmed/32270364 http://dx.doi.org/10.1007/s12325-020-01291-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Review
Krasteva, Marina Petrova
Lau, Kui Kai
Mordasini, Pasquale
Tsang, Anderson Chun On
Heldner, Mirjam Rachel
Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options
title Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options
title_full Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options
title_fullStr Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options
title_full_unstemmed Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options
title_short Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options
title_sort intracranial atherosclerotic stenoses: pathophysiology, epidemiology, risk factors and current therapy options
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467483/
https://www.ncbi.nlm.nih.gov/pubmed/32270364
http://dx.doi.org/10.1007/s12325-020-01291-4
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