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Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses

Natural Killer (NK) cells have an important role in immune responses to viruses and tumours. Integrating changes in signal transduction pathways and cellular metabolism is essential for effective NK cells responses. The glycolytic enzyme Pyruvate Kinase Muscle 2 (PKM2) has described roles in regulat...

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Detalles Bibliográficos
Autores principales:	Walls, Jessica F, Subleski, Jeff J, Palmieri, Erika M, Gonzalez-Cotto, Marieli, Gardiner, Clair M, McVicar, Daniel W, Finlay, David K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467725/ https://www.ncbi.nlm.nih.gov/pubmed/32812866 http://dx.doi.org/10.7554/eLife.59166

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